Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 5/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285264 | 0.84 | ITGB3 (0.53) | ITGB3ITGA2BBRD4GPR119DPP4 | |
| Hydrochloric Acid SCHEMBL7284606 | 0.84 | ITGB3 (0.53) | ITGB3ITGA2BIRAK4 | |
| SCHEMBL7285015 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2BBRD4IRAK4GPR119 | |
| SCHEMBL7283463 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2BBRD4IRAK4GPR119 | |
| SCHEMBL8884076 | 0.84 | ITGB3 (0.52) | ITGB3ITGA2BBRD4GPR119DPP4 | |
| SCHEMBL7277677 | 0.82 | ITGB3 (0.46) | ITGB3ITGA2BBRD4IRAK4GPR119 | |
| SCHEMBL7275877 | 0.82 | ITGB3 (0.46) | ITGB3ITGA2BBRD4IRAK4GPR119 | |
| SCHEMBL7323680 | 0.78 | ITGB3 (0.47) | ITGB3ITGA2BGPR119 | |
| SCHEMBL7318086 | 0.78 | ITGB3 (0.47) | ITGB3ITGA2BIRAK4 | |
| SCHEMBL7277406 | 0.77 | ITGB3 (0.47) | ITGB3ITGA2BIRAK4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528369-B1 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | BOEHRINGER INGELHEIM PHARMA (DE) | 1999-11-24 | — | — | EP | disclosed |
| US-5455348-A | Anticoagulants | Thomae, Karl (DE) | 1995-10-03 | — | — | US | disclosed |
| EP-0528369-A2 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-02-24 | — | — | EP | disclosed |