SCHEMBL1305745

SCHEMBL1305745

Cc1ccc(S(=O)(=O)N[C@@H](CCCCN)C(=O)C(=O)CCl)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 4/20 0.56
MMP9 P14780 2/20 0.56
PLAU P00749 4/20 0.47
HPN P05981 4/20 0.47
ITGB3 P05106 1/20 0.45
ITGA2B P08514 1/20 0.45
TDP1 Q9NUW8 1/20 0.44
SLC1A3 P43003 1/20 0.43
SLC1A2 P43004 1/20 0.43
SLC1A1 P43005 1/20 0.43
CA2 P00918 4/20 0.43
CA9 Q16790 3/20 0.43
CA12 O43570 2/20 0.43
CA1 P00915 3/20 0.42
CA7 P43166 1/20 0.42
MMP13 P45452 2/20 0.41
MMP1 P03956 1/20 0.41
MMP8 P22894 1/20 0.41
CA14 Q9ULX7 1/20 0.41
MMP3 P08254 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1305743 1.00 MMP2 (0.56) MMP2MMP9PLAUHPNITGB3
SCHEMBL200245 0.89 MMP2 (0.57) MMP2MMP9PLAUHPNITGB3
SCHEMBL200247 0.89 MMP2 (0.57) MMP2MMP9PLAUHPNITGB3
Hydrochloric Acid SCHEMBL11406948 0.88 MMP2 (0.56) MMP2MMP9PLAUHPNITGB3
Hydrochloric Acid SCHEMBL920895 0.88 MMP2 (0.56) MMP2MMP9PLAUHPNITGB3
Hydrochloric Acid SCHEMBL15537019 0.87 MMP2 (0.55) MMP2MMP9PLAUHPNITGB3
SCHEMBL28509074 0.86 MMP2 (0.60) MMP2MMP9PLAUHPNITGB3
SCHEMBL77677 0.86 MMP9 (0.67) MMP2MMP9PLAUHPNITGB3
SCHEMBL2038720 0.86 MMP9 (0.67) MMP2MMP9PLAUHPNITGB3
Hydrochloric Acid SCHEMBL1499337 0.85 MMP9 (0.65) MMP2MMP9PLAUHPNITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 252 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12203936-B2 Detection of glutathionylated proteins UNIVERSITEIT MAASTRICHT (NL) 2025-01-21 US claimed
US-20210311057-A1 DETECTION OF GLUTATHIONYLATED PROTEINS THE UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2021-10-07 US claimed
US-20180224452-A1 DETECTION OF GLUTATHIONYLATED PROTEINS THE UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2018-08-09 US claimed
US-20150056633-A1 DETECTION OF GLUTATHIONYLATED PROTEINS THE UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2015-02-26 US claimed
US-8512679-B2 Glassy compositions ELWHA LLC (US) 2013-08-20 US claimed
US-20120225011-A1 Glassy compositions Elwha LLC, a limited liability company of the State of Delaware 2012-09-06 US claimed
US-20080014595-A1 Detection of glutathionylated proteins THE UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2008-01-17 US claimed
WO-2007087365-A2 DETECTION OF GLUTATHIONYLATED PROTEINS UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2007-08-02 WO claimed
WO-2005101019-A2 DETECTION OF NITROSYLATED PROTEINS UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2005-10-27 WO claimed
US-5731198-A COMPRISING AN ENZYME INHIBITOR SUPPORTED ON A POROUS MEMBER EMERALD BIOMEDICAL SCIENCES, INC. (US) 1998-03-24 US claimed
US-5385825-A An enzyme inhibitor consisting of blood, ethylenediamine tetraacetic acid and at least one compound from N-tosyl-lysyl chloromethylketone and N-tosyl-phenylalanyl chloromethylketone ; radioimmunoassay detecting a protein or hormone analyte EMERALD BIOMEDICAL SCIENCES, INC. (US) 1995-01-31 US claimed
EP-0230670-A2 Novel host E. coli and use thereof SUNTORY LIMITED (JP) 1987-08-05 EP claimed
JP-4182423-A None JP disclosed
US-20260124259-A1 STAPHYLOCOCCUS PHAGE COMPOSITIONS AND COCKTAILS THEREOF Locus Biosciences, Inc. (US) 2026-05-07 US disclosed
US-20260115275-A1 RIBOZYME-ACTIVATED RNA CONSTRUCTS AND USES THEREOF UNIV CALIFORNIA (US) 2026-04-30 US disclosed
EP-4727556-A2 SEQUESTRANT COMPOUNDS FOR ALPHA 2 ADRENERGIC AGONISTS Clear Scientific, Inc. (US) 2026-04-22 EP disclosed
US-4582821-A CONTACTING TUMOR CELLS WITH A PEPTIDE OR AMINO ACID HALO=METHYL KETONE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-04-15 US disclosed
EP-0038357-A4 HYDROLYTIC ENZYME-ACTIVATIBLE PRO-DRUGS. UNIV ILLINOIS (US) 1982-03-22 EP disclosed
EP-0038357-A1 HYDROLYTIC ENZYME-ACTIVATIBLE PRO-DRUGS University of Illinois Foundation (US) 1981-10-28 EP disclosed
WO-1981001145-A1 HYDROLYTIC ENZYME-ACTIVATIBLE PRO-DRUGS UNIV ILLINOIS (US) 1981-04-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115275-A1 RIBOZYME-ACTIVATED RNA CONSTRUCTS AND USES THEREOF RNGTT, RNASE1, UPF1 MMP2 751/4885MMP9 2287/4885PLAU 156/4885
US-20260124259-A1 STAPHYLOCOCCUS PHAGE COMPOSITIONS AND COCKTAILS THEREOF SPOUT1, NOP2, LSM8 MMP2 1761/4885MMP9 1874/4885PLAU 1690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.