Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21375648 | 0.81 | SIGMAR1 (0.60) | ACHEOPRM1SIGMAR1DRD2HTR2A | |
| SCHEMBL7139857 | 0.79 | CHRM2 (0.48) | ACHEOPRM1SIGMAR1HTR2ABCHE | |
| SCHEMBL5859715 | 0.79 | KDM4E (0.57) | ACHEOPRM1SIGMAR1DRD2HTR2A | |
| SCHEMBL2108897 | 0.79 | ACHE (0.66) | ACHEOPRM1SIGMAR1DRD2HTR2A | |
| SCHEMBL8791969 | 0.78 | DRD2 (0.67) | ACHEOPRM1SIGMAR1DRD2HTR2A | |
| Hydrochloric Acid SCHEMBL2976109 | 0.77 | ACHE (0.64) | ACHEOPRM1SIGMAR1DRD2HTR2A | |
| SCHEMBL28173289 | 0.77 | ACHE (0.64) | ACHEOPRM1SIGMAR1DRD2HTR2A | |
| SCHEMBL5570638 | 0.76 | ACHE (0.62) | ACHEOPRM1SIGMAR1DRD2HTR2A | |
| SCHEMBL19311894 | 0.76 | ACHE (0.62) | ACHEOPRM1SIGMAR1DRD2HTR2A | |
| SCHEMBL784863 | 0.75 | SIGMAR1 (0.68) | ACHEOPRM1SIGMAR1DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |