Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7296669 | 0.77 | GPR84 (0.44) | NOTUMGPR84MMP1MMP9MMP12 | |
| SCHEMBL11874949 | 0.67 | ALDH1A1 (0.38) | — | |
| SCHEMBL11587931 | 0.66 | MEN1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL11880048 | 0.65 | ALDH1A1 (0.36) | — | |
| SCHEMBL7294301 | 0.65 | GPR84 (0.36) | NOTUMGPR84MMP1MMP2MMP9 | |
| SCHEMBL26986362 | 0.62 | GPR84 (0.50) | NOTUMGPR84MAP2K1MMP1MMP2 | |
| SCHEMBL8535240 | 0.61 | NOTUM (0.68) | NOTUMGPR84MAP2K1MMP1MMP2 | |
| SCHEMBL11578621 | 0.59 | ALDH1A1 (0.38) | — | |
| SCHEMBL10891976 | 0.58 | SIGMAR1 (0.40) | — | |
| SCHEMBL2632725 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4863938-A | Pyridine derivatives and their use as nootropic agents | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | claimed |
| EP-0239533-B1 | PYRIDINE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-09-16 | — | — | EP | disclosed |
| US-4863938-A | Pyridine derivatives and their use as nootropic agents | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |