Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 8/20 | 0.44 |
| ▸ | REN | P00797 | 5/20 | 0.44 |
| ▸ | CTSB | P07858 | 4/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716091 | 0.91 | REN (0.44) | CTSLRENCTSBCASP3CTSS | |
| SCHEMBL10718613 | 0.86 | CTSL (0.45) | CTSLRENCTSBCASP3CTSS | |
| SCHEMBL10718584 | 0.83 | REN (0.46) | CTSLRENCTSBCASP3CTSS | |
| SCHEMBL7283203 | 0.83 | CTSL (0.43) | CTSLRENCTSBCASP3CTSS | |
| SCHEMBL7274969 | 0.83 | CTSL (0.45) | CTSLRENCTSBCASP3CTSS | |
| SCHEMBL10718460 | 0.82 | REN (0.47) | CTSLRENCTSBCASP3CTSS | |
| SCHEMBL7274934 | 0.82 | REN (0.45) | CTSLRENCTSBCASP3CTSS | |
| SCHEMBL7286074 | 0.82 | CTSL (0.42) | CTSLRENCTSBCASP3CTSS | |
| SCHEMBL10762553 | 0.82 | CTSL (0.45) | CTSLRENCTSBCASP3CTSS | |
| SCHEMBL7277678 | 0.82 | MME (0.48) | CTSLACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209897-A2 | Peptide enzyme inhibitors | MERCK & CO. INC. (US) | 1987-01-28 | — | — | EP | claimed |