Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 6/20 | 0.42 |
| ▸ | REN | P00797 | 7/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 3/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | NMBR | P28336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7277008 | 0.92 | REN (0.46) | CTSLRENCASP3CTSSCTSB | |
| SCHEMBL10715871 | 0.91 | CTSS (0.43) | RENCTSSCTSK | |
| SCHEMBL10715893 | 0.88 | REN (0.46) | CTSLRENCASP3CTSSCTSB | |
| SCHEMBL10757999 | 0.87 | REN (0.43) | CTSLRENCASP3CTSSCTSB | |
| SCHEMBL10716091 | 0.84 | REN (0.44) | CTSLRENCASP3CTSSCTSB | |
| SCHEMBL10715808 | 0.83 | CTSL (0.44) | CTSLRENCASP3CTSSCTSB | |
| SCHEMBL10718613 | 0.82 | CTSL (0.45) | CTSLRENCASP3CTSSCTSB | |
| SCHEMBL7286352 | 0.82 | CTSL (0.44) | CTSLRENCASP3CTSSCTSB | |
| SCHEMBL7286158 | 0.82 | MMP2 (0.48) | CTSLRENCASP3CTSBCTSK | |
| SCHEMBL10718584 | 0.82 | REN (0.46) | CTSLRENCASP3CTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210545-A2 | Phosphorous containing enzyme inhibitors | MERCK & CO. INC. (US) | 1987-02-04 | — | — | EP | disclosed |
| EP-0209897-A2 | Peptide enzyme inhibitors | MERCK & CO. INC. (US) | 1987-01-28 | — | — | EP | disclosed |