Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.45 |
| ▸ | REN | P00797 | 3/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | MME | P08473 | 4/20 | 0.42 |
| ▸ | ECE1 | P42892 | 4/20 | 0.42 |
| ▸ | CTSB | P07858 | 3/20 | 0.41 |
| ▸ | ACE | P12821 | 4/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | MMP14 | P50281 | 2/20 | 0.39 |
| ▸ | MMP11 | P24347 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283203 | 0.93 | CTSL (0.43) | CTSLRENCASP3CTSSMME | |
| SCHEMBL7274969 | 0.92 | CTSL (0.45) | CTSLRENCASP3CTSSMME | |
| SCHEMBL7277678 | 0.92 | MME (0.48) | CTSLMMEECE1ACEMMP2 | |
| SCHEMBL10718460 | 0.91 | REN (0.47) | CTSLRENCASP3CTSSMME | |
| SCHEMBL7286158 | 0.88 | MMP2 (0.48) | CTSLRENCASP3MMEECE1 | |
| SCHEMBL10718485 | 0.88 | CTSS (0.47) | RENCTSSCTSK | |
| SCHEMBL10716091 | 0.88 | REN (0.44) | CTSLRENCASP3CTSSCTSB | |
| SCHEMBL10718705 | 0.87 | REN (0.46) | CTSLRENCASP3CTSSMME | |
| SCHEMBL7308672 | 0.87 | REN (0.46) | CTSLRENCASP3CTSSMME | |
| SCHEMBL7274934 | 0.87 | REN (0.45) | CTSLRENCASP3CTSSMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209848-A2 | Enzyme inhibitors | MERCK & CO. INC. (US) | 1987-01-28 | — | — | EP | claimed |