Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4916317 | 0.91 | ALDH1A1 (0.61) | MAPK1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL11619315 | 0.91 | ALDH1A1 (0.61) | MAPK1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL28351836 | 0.91 | ALDH1A1 (0.61) | MAPK1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL29825939 | 0.89 | ALOX15 (0.56) | MAPK1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL14421349 | 0.89 | ALDH1A1 (0.56) | CA2CA12CA9MAPK1MEN1 | |
| SCHEMBL16420023 | 0.82 | ALDH1A1 (0.50) | MAPK1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL29825951 | 0.82 | ESR1 (0.56) | MAPK1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL14905410 | 0.80 | MAPK1 (0.54) | CA2CA12CA9MAPK1MEN1 | |
| SCHEMBL728673 | 0.76 | ALDH1A1 (0.50) | MAPK1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL18380164 | 0.75 | MEN1 (0.44) | CA2CA12CA9MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016193748-A1 | COMPOSITION | THE UNIVERSITY OF BIRMINGHAM (GB) | 2016-12-08 | — | — | WO | disclosed |
| US-9078330-B2 | Highly branched dendrimers | ISIS INNOVATION LIMITED (GB) | 2015-07-07 | — | — | US | disclosed |
| US-8329316-B2 | Tetraphenylnaphalene derivatives and organic light emitting diode using the same | LG CHEM, LTD. (KR) | 2012-12-11 | — | — | US | disclosed |
| US-8329316-B2 | Tetraphenylnaphalene derivatives and organic light emitting diode using the same | LG CHEM, LTD. (KR) | 2012-12-11 | — | — | US | disclosed |
| US-20090174312-A1 | Tetraphenylnaphalene Derivatives and Organic Light Emitting Diode Using the Same | LG CHEM, LTD. (KR) | 2009-07-09 | — | — | US | disclosed |
| US-20090174312-A1 | Tetraphenylnaphalene Derivatives and Organic Light Emitting Diode Using the Same | LG CHEM, LTD. (KR) | 2009-07-09 | — | — | US | disclosed |
| US-20080211391-A1 | Highly Branched Dendrimers | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2008-09-04 | — | — | US | disclosed |
| WO-2007098440-A1 | STAR MACROMONOMERS AND POLYMERIC MATERIALS AND MEDICAL DEVICES COMPRISING SAME | BAUSCH & LOMB INCORPORATED (US) | 2007-08-30 | — | — | WO | disclosed |
| US-20070197733-A1 | Star macromonomers and polymeric materials and medical devices comprising same | BAUSCH & LOMB INCORPORATED | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090174312-A1 | Tetraphenylnaphalene Derivatives and Organic Light Emitting Diode Using the Same | CRY2, CRY1, PPOX | CA2 4674/4885CA12 3718/4885CA9 3909/4885 |
| US-20080211391-A1 | Highly Branched Dendrimers | ITGB1, PICALM, BTN3A1 | CA2 2241/4885CA12 1803/4885CA9 3352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.