Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | RAF1 | P04049 | 1/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.55 |
| ▸ | TUBB | P07437 | 1/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4689851 | 0.88 | MAPK1 (0.67) | MAPK1NPSR1GAAHTTMAPT | |
| SCHEMBL4470153 | 0.86 | MAPT (0.67) | MAPK1NPSR1GAAHTTMAPT | |
| SCHEMBL31067505 | 0.86 | MAPT (0.67) | MAPK1NPSR1GAAHTTMAPT | |
| SCHEMBL12362759 | 0.84 | TUBB4A (0.72) | MAPK1NPSR1GAAHTTMAPT | |
| SCHEMBL8679693 | 0.82 | AKR1C3 (0.50) | MAPK1NPSR1GAAHTTMAPT | |
| SCHEMBL7652799 | 0.81 | ALOX5 (0.62) | MAPK1NPSR1GAAHTTMAPT | |
| SCHEMBL730357 | 0.80 | LMNA (0.56) | MAPK1GAAHTTMAPTALDH1A1 | |
| SCHEMBL10819075 | 0.79 | MAPT (0.71) | MAPK1NPSR1GAAHTTMAPT | |
| SCHEMBL27553472 | 0.79 | MAPT (0.58) | MAPK1NPSR1GAAHTTMAPT | |
| SCHEMBL51509 | 0.78 | RXFP1 (0.79) | MAPK1NPSR1GAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138257-B1 | Bis(trialkylsiloxyphenyl)-arylfluoride imide AB2 monomers, hyperbranched polymers and nanoclay composites therefrom | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2012-03-20 | — | — | US | disclosed |
| US-8138257-B1 | Bis(trialkylsiloxyphenyl)-arylfluoride imide AB2 monomers, hyperbranched polymers and nanoclay composites therefrom | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2012-03-20 | — | — | US | disclosed |
| US-8138257-B1 | Bis(trialkylsiloxyphenyl)-arylfluoride imide AB2 monomers, hyperbranched polymers and nanoclay composites therefrom | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2012-03-20 | — | — | US | disclosed |
| US-6639042-B1 | Organic solvent soluble | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2003-10-28 | — | — | US | disclosed |
| US-6512124-B1 | N-(3,5-bis(4-hydroxybenzoyl)benzene)-4-fluoroisophthalimide. Aromatic polyimides (Pls) are well known, high-performance materials with widespread applications in the aerospace and electronics industries due to their excellent thermomechanical | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2003-01-28 | — | — | US | disclosed |