Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.54 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 3/20 | 0.53 |
| ▸ | CTSK | P43235 | 4/20 | 0.52 |
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288109 | 1.00 | ACE (0.54) | ACEACE2CTSLCTSKCNR1 | |
| SCHEMBL7361995 | 0.91 | ACE (0.55) | ACEACE2CTSLCTSKCTSS | |
| SCHEMBL349653 | 0.90 | ACE (0.52) | ACEACE2CTSLCTSKCTSS | |
| SCHEMBL844471 | 0.89 | ITGB3 (0.58) | ACEACE2CTSLCTSKCTSS | |
| SCHEMBL2185240 | 0.89 | ITGB3 (0.58) | ACEACE2CTSLCTSKCTSS | |
| SCHEMBL7758997 | 0.89 | ITGB3 (0.58) | ACEACE2CTSLCTSKCTSS | |
| SCHEMBL10688246 | 0.88 | QRFPR (0.47) | ACEACE2CNR1CNR2POLB | |
| SCHEMBL3652453 | 0.88 | POLB (0.62) | ACEACE2CTSKCNR2POLB | |
| SCHEMBL4385669 | 0.88 | POLB (0.62) | ACEACE2CTSKCNR2POLB | |
| SCHEMBL4362555 | 0.87 | CTSK (0.54) | ACEACE2CTSLCTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376012-A2 | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |