SCHEMBL728814

SCHEMBL728814

CCCCCCCCCCCCCCCC(CCO)C(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.48
OPRM1 P35372 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
TSHR P16473 1/20 0.46
CYP2D6 P10635 2/20 0.45
SPHK1 Q9NYA1 2/20 0.45
TP53 P04637 2/20 0.45
GMNN O75496 1/20 0.45
POLB P06746 1/20 0.45
THPO P40225 1/20 0.45
MTOR P42345 1/20 0.45
BLM P54132 1/20 0.45
KDM4E B2RXH2 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
MAPT P10636 1/20 0.45
CETP P11597 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23115448 1.00 LMNA (0.48) LMNAOPRM1ALDH1A1HSD17B10MEN1
SCHEMBL7205723 0.91 LMNA (0.59) LMNAOPRM1ALDH1A1HSD17B10MEN1
SCHEMBL727391 0.91 LMNA (0.59) LMNAOPRM1ALDH1A1HSD17B10MEN1
SCHEMBL454855 0.91 LMNA (0.52) LMNAOPRM1ALDH1A1HSD17B10MEN1
SCHEMBL15469680 0.91 ALDH1A1 (0.41) LMNAOPRM1ALDH1A1HSD17B10MEN1
SCHEMBL18124681 0.91 ALDH1A1 (0.41) LMNAOPRM1ALDH1A1HSD17B10MEN1
SCHEMBL727213 0.91 ALDH1A1 (0.41) LMNAOPRM1ALDH1A1HSD17B10MEN1
SCHEMBL11333881 0.88 OPRM1 (0.50) LMNAOPRM1TSHRCYP2D6SPHK1
SCHEMBL6606474 0.88 OPRM1 (0.50) LMNAOPRM1TSHRCYP2D6SPHK1
SCHEMBL28202256 0.88 OPRM1 (0.50) LMNAOPRM1TSHRCYP2D6SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2294048-B1 METHOD FOR THE PRODUCTION OF (METH)ACRYLIC ESTERS EVONIK ROEHM GMBH (DE) 2013-04-17 EP claimed
JP-2011526935-A 2011-10-20 JP claimed
EP-2294048-A2 METHOD FOR THE PRODUCTION OF (METH)ACRYLIC ESTERS Evonik Röhm GmbH (DE) 2011-03-16 EP claimed
WO-2010003709-A2 METHOD FOR THE PRODUCTION OF (METH)ACRYLIC ESTERS EVONIK RÖHM GMBH (DE) 2010-01-14 WO claimed
EP-2675874-B1 METHOD OF LUBRICATING A DRIVELINE DEVICE LUBRIZOL CORP (US) 2019-04-10 EP disclosed
US-9540582-B2 Method of lubricating a driveline device THE LUBRIZOL CORPORATION (US) 2017-01-10 US disclosed
EP-2467457-B1 LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT LUBRIZOL CORP (US) 2015-07-22 EP disclosed
EP-2891701-A1 Lubricating composition containing a corrosion inhibitor The Lubrizol Corporation (US) 2015-07-08 EP disclosed
EP-2891700-A1 Lubricating composition containing an antiwear agent The Lubrizol Corporation (US) 2015-07-08 EP disclosed
US-20150038385-A1 Method of Lubricating a Driveline Device THE LUBRIZOL CORPORATION (US) 2015-02-05 US disclosed
US-8916724-B2 Method for the production of (meth)acrylic esters EVONIK ROEHM GMBH (DE) 2014-12-23 US disclosed
US-8728996-B2 Lubricating composition containing an antiwear agent THE LUBRIZOL CORPORATION (US) 2014-05-20 US disclosed
US-8049030-B2 Method for producing (meth)acrylates EVONIK RÖHM GMBH (DE) 2011-11-01 US disclosed
US-20110130590-A1 METHOD FOR THE PRODUCTION OF (METH)ACRYLIC ESTERS EVONIK ROEHM GMBH (DE) 2011-06-02 US disclosed
EP-2294048-A2 METHOD FOR THE PRODUCTION OF (METH)ACRYLIC ESTERS Evonik Röhm GmbH (DE) 2011-03-16 EP disclosed
WO-2011022317-A1 LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT THE LUBRIZOL CORPORATION (US) 2011-02-24 WO disclosed
US-20100204509-A1 METHOD FOR PRODUCING (METH)ACRYLATES EVONIK ROEHM GMBH (DE) 2010-08-12 US disclosed
EP-2162423-A1 METHOD FOR PRODUCING (METH)ACRYLATES Evonik Röhm GmbH (DE) 2010-03-17 EP disclosed
WO-2010003709-A2 METHOD FOR THE PRODUCTION OF (METH)ACRYLIC ESTERS EVONIK RÖHM GMBH (DE) 2010-01-14 WO disclosed
WO-2009003744-A1 METHOD FOR PRODUCING (METH)ACRYLATES EVONIK RÖHM GMBH (DE) 2009-01-08 WO disclosed