Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 2/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288384 | 0.93 | SCN5A (0.34) | SCN5ASCN2AHRH4ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL10369610 | 0.86 | HRH4 (0.41) | HRH4HRH3CYP2D6 | |
| Hydrochloric Acid SCHEMBL10371446 | 0.81 | HRH4 (0.40) | HRH4HRH3KCNH2 | |
| SCHEMBL7288371 | 0.81 | ADRA2A (0.35) | ADRA2AADRA2BADRA2CCYP1A2CHRM2 | |
| Hydrochloric Acid SCHEMBL10368540 | 0.81 | GBA1 (0.40) | HRH4HRH3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10369553 | 0.81 | HRH4 (0.38) | HRH4HRH3KCNH2 | |
| Hydrochloric Acid SCHEMBL10369460 | 0.81 | GBA1 (0.39) | SCN5ASCN2AHRH4HRH3MEN1 | |
| SCHEMBL9771136 | 0.80 | HRH4 (0.37) | HRH4HRH3 | |
| SCHEMBL9828331 | 0.76 | MTNR1A (0.38) | — | |
| Hydrochloric Acid SCHEMBL10368498 | 0.76 | SSTR4 (0.46) | HRH4HRH3ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262448-A1 | Imidazolylguanidine derivatives, process for their preparation and medicines containing them | HEUMANN PHARMA GMBH & CO (DE) | 1988-04-06 | — | — | EP | disclosed |