Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA6 | P23280 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11785225 | 0.75 | ALDH1A1 (0.38) | ALDH1A1HSD17B10GPR3KDM4EGRIN2D | |
| SCHEMBL29547 | 0.71 | AHR (0.37) | ALDH1A1HSD17B10GPR3KDM4EGRIN2D | |
| SCHEMBL4466423 | 0.71 | ALDH1A1 (0.35) | ALDH1A1HSD17B10GPR3KDM4EGRIN2D | |
| SCHEMBL2230518 | 0.71 | ALDH1A1 (0.35) | ALDH1A1HSD17B10GPR3KDM4EGRIN2D | |
| SCHEMBL8588800 | 0.71 | ALDH1A1 (0.40) | ALDH1A1HSD17B10GPR3KDM4EGRIN2D | |
| SCHEMBL5067720 | 0.71 | ALDH1A1 (0.40) | ALDH1A1MAPTTDP1HTTSMN1; SMN2 | |
| SCHEMBL28824470 | 0.70 | AHR (0.35) | ALDH1A1HSD17B10GPR3KDM4EGRIN2D | |
| SCHEMBL7620124 | 0.69 | LMNA (0.33) | ALDH1A1MAPTHTR2AHTR2CLMNA | |
| SCHEMBL1972818 | 0.68 | NPC1 (0.41) | ALDH1A1HSD17B10GPR3KDM4EGRIN2D | |
| SCHEMBL10813818 | 0.68 | ALDH1A1 (0.32) | ALDH1A1HSD17B10GPR3KDM4EGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111533767-A | Tetradentate phosphine ligand and preparation method thereof, hydroformylation catalyst and reaction method, and preparation method of 1, 3-propylene glycol | 卢海元 | 2020-08-14 | — | — | CN | claimed |
| US-4870087-A | Indole containing, 2-thienyl-1,2,3,6-tetrahydropyridyls and their pharmaceutical use | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-09-26 | — | — | US | claimed |
| US-4617309-A | Sulfur-containing indole derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-10-14 | — | — | US | claimed |
| CN-111533767-A | Tetradentate phosphine ligand and preparation method thereof, hydroformylation catalyst and reaction method, and preparation method of 1, 3-propylene glycol | 卢海元 | 2020-08-14 | — | — | CN | disclosed |
| US-4870087-A | Indole containing, 2-thienyl-1,2,3,6-tetrahydropyridyls and their pharmaceutical use | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-09-26 | — | — | US | disclosed |
| EP-0121716-B1 | INDOLE DERIVATIVES | MERCK PATENT GmbH (DE) | 1987-12-09 | — | — | EP | disclosed |
| US-4617309-A | Sulfur-containing indole derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-10-14 | — | — | US | disclosed |
| EP-0105397-B1 | SULPHURIC INDOLE DERIVATIVES | MERCK PATENT GmbH (DE) | 1986-07-16 | — | — | EP | disclosed |
| EP-0121716-A1 | Indole derivatives | MERCK PATENT GmbH (DE) | 1984-10-17 | — | — | EP | disclosed |
| EP-0114603-A1 | Indole derivatives | MERCK PATENT GmbH (DE) | 1984-08-01 | — | — | EP | disclosed |
| EP-0105397-A1 | Sulphuric indole derivatives | MERCK PATENT GmbH (DE) | 1984-04-18 | — | — | EP | disclosed |