Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4307363 | 0.94 | HDAC3 (0.57) | PLA2G2AMTNR1AMTNR1BHDAC3HDAC1 | |
| SCHEMBL28519834 | 0.92 | TDP1 (0.51) | PLA2G2AMTNR1AMTNR1BTDP1KMT2A | |
| SCHEMBL4304885 | 0.91 | HDAC3 (0.54) | PLA2G2AMTNR1AMTNR1BHDAC3HDAC1 | |
| SCHEMBL8902098 | 0.89 | THRA (0.53) | PLA2G2AHDAC3HDAC1HDAC2TDP1 | |
| SCHEMBL27009292 | 0.87 | TDP1 (0.64) | MTNR1AMTNR1BHDAC3HDAC1HDAC2 | |
| SCHEMBL4057376 | 0.86 | KDM4E (0.50) | TDP1KMT2AMEN1KDM4ECYP1A2 | |
| SCHEMBL7290141 | 0.86 | KDM4E (0.51) | PLA2G2AMTNR1AMTNR1BHDAC3HDAC1 | |
| SCHEMBL16482859 | 0.86 | MAOA (0.54) | PLA2G2AHDAC3HDAC1HDAC2TDP1 | |
| SCHEMBL11353074 | 0.84 | MTNR1A (0.49) | PLA2G2AMTNR1AMTNR1BHDAC3HDAC1 | |
| SCHEMBL7951260 | 0.84 | PARP15 (0.51) | MTNR1AMTNR1BHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240019746-A1 | ULTRA-HIGH-POLARITY CHIRAL LIQUID CRYSTAL MATERIAL, LIQUID CRYSTAL LASER AND PREPARATION METHOD THEREFOR | SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) | 2024-01-18 | — | — | US | disclosed |
| US-20240019746-A1 | ULTRA-HIGH-POLARITY CHIRAL LIQUID CRYSTAL MATERIAL, LIQUID CRYSTAL LASER AND PREPARATION METHOD THEREFOR | SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) | 2024-01-18 | — | — | US | disclosed |
| CN-112322306-B | Ultrahigh-polarity chiral liquid crystal material, liquid crystal laser and preparation method thereof | 华南理工大学 | 2022-05-24 | — | — | CN | disclosed |
| WO-2022089501-A1 | ULTRA-HIGH-POLARITY CHIRAL LIQUID CRYSTAL MATERIAL, LIQUID CRYSTAL LASER AND PREPARATION METHOD THEREFOR | 华南理工大学 | 2022-05-05 | — | — | WO | disclosed |
| CN-112375168-B | Side chain rod-shaped polar liquid crystal polymer, preparation method thereof and application thereof in nonlinear optical field | 华南理工大学 | 2022-03-29 | — | — | CN | disclosed |
| CN-112375168-A | Side chain rod-shaped polar liquid crystal polymer, preparation method thereof and application thereof in nonlinear optical field | 华南理工大学 | 2021-02-19 | — | — | CN | disclosed |
| CN-112342032-A | Rod-like polar liquid crystal molecule, preparation method thereof and rod-like polar nematic liquid crystal | 华南理工大学 | 2021-02-09 | — | — | CN | disclosed |
| CN-112322306-A | Ultrahigh-polarity chiral liquid crystal material, liquid crystal laser and preparation method thereof | 华南理工大学 | 2021-02-05 | — | — | CN | disclosed |
| US-6200980-B1 | ADMINISTERING PHENYL PURINONE COMPOUND FOR TREATING PRECANCEROUS LEISONS | CELL PATHWAYS, INC. | 2001-03-13 | — | — | US | disclosed |
| US-5597841-A | 2-saccharinylmethyl aryl carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use thereof | STERLING WINTHROP, INC. (US) | 1997-01-28 | — | — | US | disclosed |
| EP-0594257-B1 | 2-Saccharinylmethyl aryl carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use thereof | STERLING WINTHROP INC (US) | 1996-07-10 | — | — | EP | disclosed |
| US-5512589-A | TREATING DEGENERATIVE DISEASES | STERLING WINTHROP INC. (US) | 1996-04-30 | — | — | US | disclosed |
| EP-0352960-B1 | Purine compounds, process for their preparation and pharmaceutical compositions | SMITH KLINE FRENCH LAB (GB) | 1994-10-26 | — | — | EP | disclosed |
| EP-0594257-A1 | 2-Saccharinylmethyl aryl carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use thereof | STERLING WINTHROP INC. (US) | 1994-04-27 | — | — | EP | disclosed |
| US-5306818-A | Treating degenerative diseases such as emphysema, rheumatoid arthritis and pancreatitis | STERLING WINTHROP INC. (US) | 1994-04-26 | — | — | US | disclosed |
| US-5073559-A | 2-Substituted purinone having phosphodiesterase inhibitory activity | SMITH KLINE & FRENCH LABORATORIES, LTD. (GB) | 1991-12-17 | — | — | US | disclosed |
| EP-0352960-A2 | Purine compounds, process for their preparation and pharmaceutical compositions | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1990-01-31 | — | — | EP | disclosed |
| US-4764525-A | N-1H-tetrazol-5-ylbenzamides having use as antiallergy and antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1988-08-16 | — | — | US | disclosed |