Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7296477 | 0.86 | ACE (0.50) | MEN1CYP1A2KMT2A | |
| SCHEMBL10489583 | 0.81 | FKBP1A (0.52) | — | |
| SCHEMBL7513191 | 0.81 | CTSL (0.67) | CTSLCTSKCTSBCTSS | |
| SCHEMBL7511180 | 0.79 | MEN1 (0.63) | MEN1CYP1A2KMT2A | |
| SCHEMBL3169636 | 0.79 | MEN1 (0.63) | MEN1CYP1A2KMT2A | |
| SCHEMBL6060180 | 0.79 | MEN1 (0.63) | MEN1CYP1A2KMT2A | |
| SCHEMBL21787658 | 0.78 | MEN1 (0.53) | MEN1CYP1A2KMT2A | |
| SCHEMBL7512878 | 0.75 | CTSL (0.65) | CTSLCTSKCTSBCTSS | |
| SCHEMBL10420650 | 0.73 | TACR1 (0.57) | KMT2ACTSLTACR1CTSKCTSB | |
| SCHEMBL7513937 | 0.72 | MEN1 (0.55) | MEN1CYP1A2KMT2ACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4876359-A | HYPOTENSIVE, ANGIOTENSIN ENZYME INHIBITOR | SS PHARMACEUTICAL CO., LTD. (JP) | 1989-10-24 | — | — | US | disclosed |
| EP-0266568-A2 | Novel gamma-butyrolactone derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |