Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 10/20 | 0.52 |
| ▸ | ACE | P12821 | 5/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.45 |
| ▸ | PREP | P48147 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295973 | 0.88 | FKBP1A (0.52) | FKBP1AACEPREP | |
| SCHEMBL7288696 | 0.81 | MEN1 (0.52) | — | |
| SCHEMBL6439093 | 0.80 | ACE (0.62) | FKBP1AACECTRB1 | |
| SCHEMBL7355192 | 0.79 | ACE (0.57) | FKBP1AACE | |
| SCHEMBL7424465 | 0.78 | FKBP1A (0.56) | FKBP1AACECTRB1 | |
| SCHEMBL6434816 | 0.78 | FKBP1A (0.56) | FKBP1AACECTRB1 | |
| SCHEMBL8365677 | 0.77 | ACE (0.57) | FKBP1AACE | |
| SCHEMBL8364232 | 0.77 | ACE (0.57) | FKBP1AACE | |
| SCHEMBL10404568 | 0.77 | ACE (0.53) | FKBP1AACECTRB1 | |
| SCHEMBL6436340 | 0.77 | ACE (0.59) | FKBP1AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4876359-A | HYPOTENSIVE, ANGIOTENSIN ENZYME INHIBITOR | SS PHARMACEUTICAL CO., LTD. (JP) | 1989-10-24 | — | — | US | disclosed |