Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | USP8 | P40818 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273707 | 0.84 | L3MBTL1 (0.45) | L3MBTL1GAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL20853408 | 0.84 | L3MBTL1 (0.45) | L3MBTL1GAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL15559998 | 0.79 | CXCL8 (0.44) | L3MBTL1GAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL20529654 | 0.76 | CTSD (0.41) | L3MBTL1GAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2551195 | 0.76 | L3MBTL1 (0.46) | L3MBTL1GAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL1343672 | 0.74 | TSHR (0.44) | L3MBTL1GAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27866804 | 0.73 | ALOX15 (0.36) | L3MBTL1GAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2838988 | 0.73 | CXCL8 (0.45) | L3MBTL1ALDH1A1KDM4ETSHRMAPT | |
| SCHEMBL8503015 | 0.72 | L3MBTL1 (0.42) | L3MBTL1GAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11604414 | 0.72 | TSHR (0.46) | L3MBTL1GAAALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567264-A | ADRENERGIC BLOCKING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1986-01-28 | — | — | US | disclosed |
| EP-0126449-A1 | Cardioselective aryloxy- and arylthio-hydroxypropyl piperazinyl acetanilides wich affect calcium entry | SYNTEX (U.S.A.) INC. (US) | 1984-11-28 | — | — | EP | disclosed |