Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1154812 | 0.83 | GSK3B (0.57) | GSK3BRAB9ANPC1MAPTESR2 | |
| SCHEMBL7290567 | 0.81 | CA1 (0.54) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2064455 | 0.81 | NPC1 (0.58) | GSK3BRAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL863102 | 0.81 | ESR2 (0.59) | RAB9ANPC1MAPTESR2ALDH1A1 | |
| SCHEMBL9688423 | 0.81 | GSK3B (0.42) | GSK3BRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL3041661 | 0.80 | ALDH1A1 (0.62) | RAB9ANPC1MAPTESR2SMN1; SMN2 | |
| SCHEMBL20135229 | 0.79 | MAPT (0.62) | RAB9ANPC1MAPTESR2SMN1; SMN2 | |
| SCHEMBL246263 | 0.79 | HDAC3 (0.66) | GSK3BHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL19219873 | 0.79 | NPC1 (0.55) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10796669 | 0.79 | HAO1 (0.46) | GSK3BHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0166609-A2 | Aryl derivatives of heterobicyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-01-02 | — | — | EP | disclosed |