Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29483355 | 0.86 | KDM4E (0.54) | GAAMAPK1KDM4EHPGDALDH1A1 | |
| SCHEMBL5302770 | 0.83 | KDM4E (0.45) | GAAMAPK1KDM4EHPGDCYP1A2 | |
| SCHEMBL7148312 | 0.77 | SMN1; SMN2 (0.49) | MAPK1KDM4EHPGDALDH1A1L3MBTL1 | |
| SCHEMBL12713296 | 0.75 | KDM4E (0.49) | GAAMAPK1KDM4EHPGDCYP1A2 | |
| SCHEMBL6312839 | 0.71 | ALDH1A1 (0.64) | MAPK1KDM4EHPGDALDH1A1MAPT | |
| SCHEMBL10184561 | 0.71 | KDM4E (0.43) | GAAMAPK1KDM4EHPGDALDH1A1 | |
| SCHEMBL27549630 | 0.70 | KDM4C (0.43) | GAAMAPK1KDM4EHPGDALDH1A1 | |
| SCHEMBL14736240 | 0.69 | TSHR (0.43) | GAAMAPK1KDM4EHPGDCYP1A2 | |
| SCHEMBL11747736 | 0.68 | P2RX7 (0.62) | GAAMAPK1KDM4EHPGDALDH1A1 | |
| SCHEMBL7141368 | 0.66 | NPC1 (0.57) | GAAKDM4EHPGDCYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324420-B2 | Process for producing acrylonitrile compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-12-04 | — | — | US | disclosed |
| CN-101891682-B | Process for producing acrylonitrile compound | NISSAN CHEMICAL IND LTD | 2012-07-04 | — | — | CN | disclosed |
| US-8138368-B2 | Process for producing acrylonitrile compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-03-20 | — | — | US | disclosed |
| US-20110313173-A1 | Process for producing acrylonitrile compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-12-22 | — | — | US | disclosed |
| CN-101284814-B | Method for producing acrylonitrile compound | NISSAN CHEMICAL IND LTD | 2011-08-17 | — | — | CN | disclosed |
| CN-101891682-A | The manufacture method of acrylonitrile compound | NISSAN CHEMICAL IND LTD | 2010-11-24 | — | — | CN | disclosed |
| US-20100029951-A1 | Process for producing acrylonitrile compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-02-04 | — | — | US | disclosed |
| US-7649104-B2 | producing 3-acyloxyacrylonitrile compound as an agricultural and horticultural pesticide; using the produced 3-oxopropionitrile compound as the intermediate | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-01-19 | — | — | US | disclosed |
| CN-101284814-A | Method for producing acrylonitrile compound | NISSAN CHEMICAL IND LTD (JP) | 2008-10-15 | — | — | CN | disclosed |
| CN-100402503-C | Method for producing acrylonitrile compound | NISSAN CHEMICAL IND LTD (JP) | 2008-07-16 | — | — | CN | disclosed |
| US-20060178523-A1 | Process for producing acrylonitrile compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2006-08-10 | — | — | US | disclosed |
| CN-1768042-A | Method for producing acrylonitrile compound | NISSAN CHEMICAL IND LTD (JP) | 2006-05-03 | — | — | CN | disclosed |
| US-6642234-B1 | Insecticides, acaricides, nematocides, herbicides and fungicides, | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2003-11-04 | — | — | US | disclosed |
| EP-1142882-A9 | ACRYLONITRILE COMPOUNDS | Nissan Chemical Industries, Ltd. (JP) | 2002-10-02 | — | — | EP | disclosed |
| CN-1333759-A | Acrylonitrile compounds | NISSAN CHEMICAL IND LTD (JP) | 2002-01-30 | — | — | CN | disclosed |
| EP-1142882-A1 | ACRYLONITRILE COMPOUNDS | Nissan Chemical Industries, Ltd. (JP) | 2001-10-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178523-A1 | Process for producing acrylonitrile compound | ZYX, ACR, ZDHHC9 | GAA 1787/4885MAPK1 2333/4885KDM4E 1437/4885 |
| US-20110313173-A1 | Process for producing acrylonitrile compound | ZYX, ACR, ZDHHC9 | GAA 1787/4885MAPK1 2333/4885KDM4E 1437/4885 |
| US-20100029951-A1 | Process for producing acrylonitrile compound | ZYX, ACR, ZDHHC9 | GAA 1787/4885MAPK1 2333/4885KDM4E 1437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.