Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7293361 | 0.93 | SLC7A5 (0.53) | LCKNOD1EGFRKDM4EUSP2 | |
| SCHEMBL11850734 | 0.84 | LCK (0.53) | LCKEGFRKDM4EUSP2FYN | |
| SCHEMBL11854802 | 0.84 | LCK (0.55) | LCKEGFRKDM4EUSP2FYN | |
| Hydrochloric Acid SCHEMBL7294546 | 0.81 | ALDH1A1 (0.44) | NOD1ALOX15ALDH1A1KMT2APOLB | |
| Etilevodopa SCHEMBL29634876 | 0.81 | ALOX15 (0.64) | LCKEGFRKDM4EUSP2FYN | |
| Etilevodopa SCHEMBL1069939 | 0.81 | ALOX15 (0.64) | LCKEGFRKDM4EUSP2FYN | |
| Etilevodopa SCHEMBL584493 | 0.81 | ALOX15 (0.64) | LCKEGFRKDM4EUSP2FYN | |
| Hydrochloric Acid SCHEMBL7301902 | 0.81 | ALOX15 (0.52) | NOD1ALOX15ALDH1A1POLB | |
| SCHEMBL11856676 | 0.81 | LCK (0.49) | LCKEGFRKDM4EUSP2FYN | |
| SCHEMBL15275678 | 0.80 | LCK (0.52) | LCKEGFRKDM4EUSP2FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352815-B1 | PRODRUGS OF DOPAMINE | ZAMBON GROUP S.p.A. (IT) | 1993-05-19 | — | — | EP | disclosed |
| US-5013753-A | Prodrugs of dopamine | SIMES (IT) | 1991-05-07 | — | — | US | disclosed |
| EP-0352815-A1 | Prodrugs of dopamine | ZAMBON GROUP S.p.A. (IT) | 1990-01-31 | — | — | EP | disclosed |