Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PGA5 | P0DJD9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744038 | 0.95 | CTSD (0.39) | REN | |
| SCHEMBL9822366 | 0.89 | REN (0.43) | RENPGA5 | |
| SCHEMBL9741566 | 0.88 | CTSD (0.40) | REN | |
| SCHEMBL9822122 | 0.86 | REN (0.49) | RENPGA5 | |
| SCHEMBL7303899 | 0.84 | CTSD (0.42) | REN | |
| SCHEMBL9822410 | 0.82 | REN (0.52) | RENPGA5 | |
| SCHEMBL10421167 | 0.76 | PSEN1 (0.38) | REN | |
| SCHEMBL10632103 | 0.75 | CTSD (0.48) | REN | |
| SCHEMBL10422410 | 0.72 | APP (0.36) | REN | |
| SCHEMBL10421152 | 0.72 | APP (0.36) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356796-A2 | Aminomethyl peptides, production process and their use as medicaments | BAYER AG (DE) | 1990-03-07 | — | — | EP | disclosed |