Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 6/20 | 0.40 |
| ▸ | REN | P00797 | 14/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303899 | 0.96 | CTSD (0.42) | CTSDREN | |
| SCHEMBL9744038 | 0.93 | CTSD (0.39) | CTSDREN | |
| SCHEMBL9822366 | 0.91 | REN (0.43) | CTSDREN | |
| SCHEMBL9822122 | 0.90 | REN (0.49) | CTSDREN | |
| SCHEMBL7292919 | 0.88 | REN (0.39) | REN | |
| SCHEMBL9822410 | 0.86 | REN (0.52) | REN | |
| SCHEMBL10632103 | 0.77 | CTSD (0.48) | CTSDREN | |
| SCHEMBL10421167 | 0.76 | PSEN1 (0.38) | REN | |
| SCHEMBL10436048 | 0.73 | OPRK1 (0.55) | — | |
| SCHEMBL10436047 | 0.73 | OPRK1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122610-A | Renin inhibitor intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-16 | — | — | US | disclosed |