Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.48 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.48 |
| ▸ | SCN1A | P35498 | 3/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 5/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | THPO | P40225 | 2/20 | 0.46 |
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7289657 | 0.85 | PNMT (0.50) | HRH3SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL9812324 | 0.85 | SLC6A2 (0.63) | HRH3SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL7276674 | 0.84 | SLC6A2 (0.51) | HRH3SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL5161949 | 0.81 | HRH1 (0.67) | HRH3SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL10368383 | 0.81 | SLC6A2 (0.68) | HRH3SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL29360970 | 0.81 | CHRM2 (0.68) | HRH3SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL7288069 | 0.81 | SLC6A2 (0.55) | HRH3SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL9574865 | 0.81 | CHRM2 (0.68) | HRH3SLC6A2SLC6A4SLC6A3KCNH2 | |
| Hydrochloric Acid SCHEMBL4433367 | 0.80 | HRH1 (0.64) | HRH3SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL11049849 | 0.79 | FFAR1 (0.48) | HRH3SLC6A2SLC6A4CHRM2SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262448-B1 | IMIDAZOLYLGUANIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | HEUMANN PHARMA GMBH & CO (DE) | 1991-12-18 | — | — | EP | disclosed |
| US-4912119-A | Cardiovascular disorders | HEUMANN PHARMA GMBH & CO. (DE) | 1990-03-27 | — | — | US | disclosed |
| EP-0262448-A1 | Imidazolylguanidine derivatives, process for their preparation and medicines containing them | HEUMANN PHARMA GMBH & CO (DE) | 1988-04-06 | — | — | EP | disclosed |