Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.63 |
| ▸ | PROC | P04070 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294378 | 0.92 | MME (0.56) | MMEPROCNPC1RAB9AMEN1 | |
| SCHEMBL7300905 | 0.83 | MME (0.64) | MMEPROCMMP8HDAC9F2 | |
| SCHEMBL7301300 | 0.82 | MME (0.40) | MMENPC1RAB9ASMN1; SMN2MMP8 | |
| SCHEMBL7303622 | 0.80 | MME (0.43) | MMENPC1RAB9AMEN1KMT2A | |
| SCHEMBL7292698 | 0.78 | MME (0.38) | MMENPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL7301621 | 0.77 | MME (1.00) | MMEMMP8HDAC9HPGD | |
| SCHEMBL7295886 | 0.77 | HTR2C (0.40) | MMEMMP8 | |
| SCHEMBL7297983 | 0.76 | MME (0.36) | MMENPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7303084 | 0.75 | MME (0.57) | MMEPROCMMP8 | |
| SCHEMBL7294410 | 0.73 | GHSR (0.36) | MMESMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252601-A | 2-mercaptomethylene-tetrahydronaphthalene and indane-2-carboxamide derivatives as enkephalinase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0516980-A1 | Novel 2-mercaptomethylene-tetrahydronaphthalene and indane-2-carboxamide derivatives as enkephalinase inhibitors | MERRELL PHARMACEUTICALS INC. (US) | 1992-12-09 | — | — | EP | disclosed |