Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302832 | 0.83 | GAA (0.38) | ALDH1A1KMT2AKDM4EDHFRCYP2C19 | |
| SCHEMBL7296622 | 0.80 | GAA (0.36) | ALDH1A1KDM4ELMNADHFRCYP2C19 | |
| SCHEMBL7294598 | 0.79 | CYP26A1 (0.44) | ALDH1A1KMT2AKDM4ECA1CA2 | |
| SCHEMBL7304044 | 0.78 | POLB (0.31) | POLB | |
| SCHEMBL7296333 | 0.77 | ADRA1D (0.39) | KDM4ECYP2C19CYP2C9MAPK1GAA | |
| SCHEMBL7305086 | 0.77 | ADRA1D (0.39) | KDM4ECYP2C19CYP2C9MAPK1GAA | |
| SCHEMBL7302057 | 0.77 | ADRA1D (0.39) | KDM4ECYP2C19CYP2C9MAPK1GAA | |
| SCHEMBL7294376 | 0.74 | ALDH1A1 (0.32) | ALDH1A1KMT2AKDM4ECYP2C19MEN1 | |
| SCHEMBL7301966 | 0.73 | HTR1A (0.34) | ALDH1A1KDM4ECYP2C19CYP3A4MAPK1 | |
| SCHEMBL7295766 | 0.71 | ADRA1D (0.34) | ALDH1A1KDM4ECYP2C19CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |