Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7293185 | 0.82 | TSHR (0.36) | HTR1AHTR7ALDH1A1KDM4EMAPT | |
| SCHEMBL7304146 | 0.76 | LMNA (0.33) | FKBP1A | |
| SCHEMBL7304238 | 0.75 | PREP (0.53) | HTR1AHTR7 | |
| SCHEMBL7304241 | 0.75 | PREP (0.53) | HTR1AHTR7 | |
| SCHEMBL7302819 | 0.73 | PREP (0.31) | ALDH1A1KDM4E | |
| SCHEMBL7301136 | 0.73 | MEN1 (0.32) | ALDH1A1KDM4E | |
| SCHEMBL7295136 | 0.73 | ALDH1A1 (0.38) | ALDH1A1KDM4EMAPTCYP3A4MAPK1 | |
| SCHEMBL7302892 | 0.72 | PREP (0.42) | HTR1AHTR7ALDH1A1KDM4EFKBP1A | |
| SCHEMBL7292875 | 0.70 | ALDH1A1 (0.46) | ALDH1A1KDM4EFKBP1A | |
| SCHEMBL9048411 | 0.69 | PREP (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |