Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | GALR3 | O60755 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7245174 | 0.81 | NPC1 (0.76) | NPC1MAPTRAB9AMAPK1ALDH1A1 | |
| SCHEMBL4559509 | 0.80 | SMN1; SMN2 (0.59) | NPC1MAPTRAB9AALDH1A1HTT | |
| SCHEMBL7302329 | 0.79 | RAB9A (0.76) | NPC1RAB9AMAPK1ALDH1A1HTT | |
| SCHEMBL6705978 | 0.78 | MAPT (1.00) | NPC1MAPTRAB9AMAPK1ALDH1A1 | |
| SCHEMBL14527424 | 0.77 | RAB9A (0.63) | NPC1MAPTRAB9AMAPK1ALDH1A1 | |
| SCHEMBL6709848 | 0.76 | NPC1 (0.78) | NPC1MAPTRAB9AMAPK1ALDH1A1 | |
| SCHEMBL7301496 | 0.75 | HTT (0.73) | NPC1MAPTRAB9AMAPK1ALDH1A1 | |
| SCHEMBL7302107 | 0.74 | NPC1 (0.69) | NPC1MAPTRAB9AMAPK1ALDH1A1 | |
| SCHEMBL6169544 | 0.73 | NPC1 (0.78) | NPC1MAPTRAB9AMAPK1ALDH1A1 | |
| SCHEMBL3021071 | 0.73 | LMNA (0.64) | NPC1MAPTRAB9AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |