Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.76 |
| ▸ | GALR3 | O60755 | 1/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.76 |
| ▸ | NAMPT | P43490 | 4/20 | 0.73 |
| ▸ | NPC1 | O15118 | 5/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | TNF | P01375 | 1/20 | 0.59 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14527424 | 0.89 | RAB9A (0.63) | RAB9AGALR3MAPK1NAMPTNPC1 | |
| SCHEMBL30994893 | 0.86 | PGR (0.74) | RAB9ANPC1SMN1; SMN2TP53KMT2A | |
| SCHEMBL13167592 | 0.83 | NAMPT (0.82) | RAB9ANAMPTNPC1SMN1; SMN2TP53 | |
| SCHEMBL10150461 | 0.83 | LMNA (0.56) | RAB9AGALR3MAPK1NAMPTNPC1 | |
| SCHEMBL3872792 | 0.81 | NAMPT (0.78) | RAB9ANAMPTNPC1SMN1; SMN2KMT2A | |
| SCHEMBL789920 | 0.81 | RAB9A (0.78) | RAB9AGALR3MAPK1NAMPTNPC1 | |
| SCHEMBL12310174 | 0.80 | KMT2A (0.76) | RAB9ANPC1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL11617534 | 0.79 | RAB9A (0.75) | RAB9ANAMPTNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7295236 | 0.79 | NPC1 (0.64) | RAB9AGALR3MAPK1NAMPTNPC1 | |
| SCHEMBL3872500 | 0.78 | NAMPT (0.65) | RAB9AGALR3MAPK1NAMPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |