Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.59 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295337 | 0.85 | RAB9A (0.59) | L3MBTL1NPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL3504475 | 0.85 | SMPD1 (0.62) | L3MBTL1NPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL1715613 | 0.83 | SPHK2 (0.45) | SPHK2SPHK1L3MBTL1MAPK1MEN1 | |
| SCHEMBL7294504 | 0.81 | L3MBTL1 (0.62) | SPHK2SPHK1L3MBTL1NPC1RAB9A | |
| SCHEMBL3504608 | 0.81 | HDAC1 (0.50) | SPHK2SPHK1L3MBTL1NPC1RAB9A | |
| SCHEMBL16067423 | 0.79 | L3MBTL1 (0.72) | L3MBTL1NPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL12717111 | 0.78 | KDM4E (0.50) | L3MBTL1NPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL5165375 | 0.77 | L3MBTL1 (0.50) | SPHK2SPHK1L3MBTL1NPC1RAB9A | |
| SCHEMBL7389079 | 0.77 | TP53 (0.56) | SPHK2SPHK1L3MBTL1NPC1RAB9A | |
| SCHEMBL13130238 | 0.76 | L3MBTL1 (1.00) | L3MBTL1NPC1RAB9ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0504574-B1 | 1,2,4-Oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity and method for preparing same | WAKAMOTO PHARMA CO LTD (JP) | 1996-02-28 | — | — | EP | claimed |
| EP-0504574-B1 | 1,2,4-Oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity and method for preparing same | WAKAMOTO PHARMA CO LTD (JP) | 1996-02-28 | — | — | EP | disclosed |
| EP-0504574-A1 | 1,2,4-Oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity and method for preparing same | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1992-09-23 | — | — | EP | disclosed |