Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.58 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PPARD | Q03181 | 5/20 | 0.55 |
| ▸ | PPARA | Q07869 | 5/20 | 0.55 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3506676 | 0.87 | RAB9A (0.53) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL7297949 | 0.86 | RAB9A (0.50) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL3505981 | 0.85 | RAB9A (0.53) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL17707864 | 0.85 | NR1H4 (0.61) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL7295341 | 0.85 | SPHK2 (0.59) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL3505092 | 0.85 | L3MBTL1 (0.55) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL3504096 | 0.84 | DHFR (0.62) | L3MBTL1MAPK1TDP1SMPD1TSHR | |
| SCHEMBL3061817 | 0.84 | NR1H4 (0.64) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL3504473 | 0.83 | ACACB (0.65) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL3056578 | 0.82 | NR1H4 (0.74) | RAB9ANPC1L3MBTL1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0504574-B1 | 1,2,4-Oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity and method for preparing same | WAKAMOTO PHARMA CO LTD (JP) | 1996-02-28 | — | — | EP | claimed |
| EP-0504574-B1 | 1,2,4-Oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity and method for preparing same | WAKAMOTO PHARMA CO LTD (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5356916-A | Treating Parkinson*s disease | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1994-10-18 | — | — | US | disclosed |
| EP-0504574-A1 | 1,2,4-Oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity and method for preparing same | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1992-09-23 | — | — | EP | disclosed |