Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308284 | 0.81 | HSP90AB1 (0.47) | HSP90AB1KMT2AMEN1CYP3A4PTGS1 | |
| SCHEMBL7295697 | 0.79 | HSP90AB1 (0.55) | HSP90AB1KMT2AMEN1CYP3A4PTGS1 | |
| SCHEMBL7308290 | 0.77 | HSP90AB1 (0.52) | HSP90AB1KMT2AMEN1CYP3A4PTGS1 | |
| SCHEMBL8578355 | 0.75 | HSP90AB1 (0.46) | HSP90AB1KMT2AMEN1CYP3A4PTGS1 | |
| SCHEMBL8576831 | 0.75 | HSP90AB1 (0.42) | HSP90AB1KMT2AMEN1CYP3A4PTGS1 | |
| SCHEMBL708178 | 0.70 | L3MBTL1 (0.45) | HSP90AB1KMT2AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL7300067 | 0.70 | KMT2A (0.48) | HSP90AB1KMT2AMEN1CYP3A4PTGS1 | |
| SCHEMBL10878661 | 0.69 | CA9 (0.50) | HSP90AB1KMT2AMEN1CYP3A4PTGS1 | |
| SCHEMBL8619638 | 0.68 | ALDH1A1 (0.44) | HSP90AB1KMT2AMEN1CYP3A4PTGS1 | |
| SCHEMBL27449637 | 0.68 | HSP90AB1 (0.43) | HSP90AB1KMT2AMEN1CYP3A4PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |