Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 12/20 | 0.52 |
| ▸ | PREP | P48147 | 2/20 | 0.48 |
| ▸ | ACE | P12821 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10489583 | 0.88 | FKBP1A (0.52) | FKBP1APREPACE | |
| SCHEMBL7294043 | 0.85 | FKBP1A (0.51) | FKBP1APREPACELMNA | |
| SCHEMBL7287812 | 0.85 | FKBP1A (0.51) | FKBP1APREPACELMNA | |
| SCHEMBL7296526 | 0.83 | FKBP1A (0.48) | FKBP1APREPACELMNA | |
| SCHEMBL23502313 | 0.82 | FKBP1A (0.62) | FKBP1APREPACELMNA | |
| SCHEMBL7287091 | 0.81 | FKBP1A (0.47) | FKBP1APREPACELMNA | |
| SCHEMBL7298406 | 0.81 | ACE (0.47) | ACELMNA | |
| SCHEMBL7296029 | 0.81 | FKBP1A (0.46) | FKBP1APREPACELMNA | |
| SCHEMBL21696841 | 0.80 | FKBP1A (0.60) | FKBP1APREPACELMNA | |
| SCHEMBL7333471 | 0.80 | FKBP1A (0.60) | FKBP1APREPACELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4876359-A | HYPOTENSIVE, ANGIOTENSIN ENZYME INHIBITOR | SS PHARMACEUTICAL CO., LTD. (JP) | 1989-10-24 | — | — | US | disclosed |
| EP-0266568-A2 | Novel gamma-butyrolactone derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |