Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | SCN1A | P35498 | 2/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6369015 | 0.87 | ALDH1A1 (0.52) | LMNATSHRTP53MEN1KMT2A | |
| SCHEMBL2013038 | 0.84 | LMNA (0.55) | LMNATSHRTP53PDCD1CD274 | |
| SCHEMBL5725942 | 0.84 | LMNA (0.55) | LMNATSHRTP53PDCD1CD274 | |
| SCHEMBL6954448 | 0.83 | TSHR (0.49) | LMNATSHRTP53PDCD1CD274 | |
| SCHEMBL443825 | 0.82 | ALDH1A1 (0.54) | LMNATSHRTP53PDCD1CD274 | |
| SCHEMBL525355 | 0.82 | LMNA (0.53) | LMNATSHRTP53PDCD1CD274 | |
| SCHEMBL5726833 | 0.81 | PRKCA (0.60) | LMNATSHRTP53PDCD1CD274 | |
| SCHEMBL11572142 | 0.81 | TSHR (0.55) | LMNATSHRTP53PDCD1CD274 | |
| SCHEMBL15827354 | 0.81 | PRKCA (0.60) | LMNATSHRTP53PDCD1CD274 | |
| SCHEMBL1786404 | 0.81 | LMNA (0.51) | LMNATSHRTP53PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |