Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128505 | 0.91 | CA12 (0.46) | LMNATSHRALDH1A1PDCD1CD274 | |
| SCHEMBL25170017 | 0.90 | LMNA (0.50) | LMNATSHRTP53ALDH1A1PDCD1 | |
| SCHEMBL28350137 | 0.88 | LMNA (0.49) | LMNATSHRTP53ALDH1A1PDCD1 | |
| Terephthalic Acid SCHEMBL8439001 | 0.88 | MAPT (0.49) | TSHRTP53ALDH1A1PDCD1CD274 | |
| SCHEMBL3074456 | 0.88 | PRKCA (0.45) | LMNAALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL2061233 | 0.88 | MAPT (0.49) | TSHRTP53ALDH1A1PDCD1CD274 | |
| SCHEMBL10791097 | 0.87 | CTSK (0.54) | LMNATSHRTP53ALDH1A1MEN1 | |
| SCHEMBL27650049 | 0.87 | CTSK (0.54) | LMNATSHRTP53ALDH1A1MEN1 | |
| SCHEMBL2185343 | 0.85 | KMT2A (0.48) | LMNATP53ALDH1A1KMT2ANPC1 | |
| SCHEMBL344615 | 0.85 | TSHR (0.55) | LMNATSHRTP53ALDH1A1PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160000067-A1 | FORMULATIONS | SYNGENTA LIMITED (GB) | 2016-01-07 | — | — | US | claimed |
| CN-105001307-A | Coupling peptide chain capable of dissolving indissolvable polypeptide and application of the same in separation and purification in liquid chromatogram | SPEC CHEM INDUSTRY INC | 2015-10-28 | — | — | CN | claimed |
| CN-105001298-A | Synthesis-separation and purification method for indissolvable polypeptide | SPEC CHEM INDUSTRY INC | 2015-10-28 | — | — | CN | claimed |
| EP-2598472-A2 | FORMULATIONS | Syngenta Limited (GB) | 2013-06-05 | — | — | EP | claimed |
| WO-2012014152-A2 | FORMULATIONS | SYNGENTA LIMITED (GB) | 2012-02-02 | — | — | WO | claimed |
| CN-111557880-B | Whitening and firming plant essence care solution and preparation method thereof | 广东海通药业有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-111557880-A | Whitening and firming plant essence care solution and preparation method thereof | 广西漫迪丽生物科技有限公司 | 2020-08-21 | — | — | CN | disclosed |
| US-9807999-B2 | Formulations | SYNGENTA LIMITED (GB) | 2017-11-07 | — | — | US | disclosed |
| CN-105001307-A | Coupling peptide chain capable of dissolving indissolvable polypeptide and application of the same in separation and purification in liquid chromatogram | SPEC CHEM INDUSTRY INC | 2015-10-28 | — | — | CN | disclosed |
| CN-105001298-A | Synthesis-separation and purification method for indissolvable polypeptide | SPEC CHEM INDUSTRY INC | 2015-10-28 | — | — | CN | disclosed |
| EP-2598472-B1 | FORMULATIONS | SYNGENTA LTD (GB) | 2015-06-17 | — | — | EP | disclosed |
| CN-103265428-B | Method for preparing 4-[(3-halogenate-4-oxo) butyl] benzoic acid | SUZHOU MIRACPHARMA TECHNOLOGY CO LTD | 2014-11-26 | — | — | CN | disclosed |
| CN-103265428-A | Method for preparing 4-[(3-halogenate-4-oxo) butyl] benzoic acid | SUZHOU MINGYUE MEDICAL TECHNOLOGY CO LTD | 2013-08-28 | — | — | CN | disclosed |
| JP-2002336371-A | SPRINKLER HEAD | NOHMI BOSAI LTD | 2002-11-26 | — | — | JP | disclosed |
| US-4940134-A | TREATING USED PHOTOGRAPHIC SOLUTIONS, EVAPORATION, CONDENSATION | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1990-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160000067-A1 | FORMULATIONS | PRMT1, PRMT5, PRMT3 | LMNA 2919/4885TSHR 2009/4885TP53 2811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.