Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 7/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295272 | 0.91 | AOC3 (0.43) | AOC3GPR119HRH3MEN1KMT2A | |
| SCHEMBL7295259 | 0.91 | AOC3 (0.43) | AOC3GPR119HRH3MEN1KMT2A | |
| SCHEMBL7305518 | 0.88 | HRH3 (0.42) | AOC3GPR119HRH3MEN1KMT2A | |
| SCHEMBL7297485 | 0.85 | MEN1 (0.45) | AOC3GPR119HRH3MEN1KMT2A | |
| SCHEMBL7304758 | 0.84 | PANK3 (0.39) | AOC3GPR119HRH3MEN1KMT2A | |
| SCHEMBL7299584 | 0.83 | HRH3 (0.42) | AOC3GPR119HRH3MEN1KMT2A | |
| SCHEMBL7303451 | 0.80 | GPR119 (0.42) | AOC3GPR119HRH3MEN1KMT2A | |
| SCHEMBL7299587 | 0.79 | HRH3 (0.36) | AOC3GPR119HRH3MEN1KMT2A | |
| SCHEMBL7293154 | 0.77 | ALDH1A1 (0.34) | GPR119HRH3MEN1KMT2AITGB3 | |
| SCHEMBL7297025 | 0.76 | KMT2A (0.41) | GPR119MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609282-A1 | CYCLOHEXANEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-08-10 | — | — | EP | disclosed |
| WO-1993008181-A1 | CYCLOHEXANEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-04-29 | — | — | WO | disclosed |
| EP-0537980-A1 | Cyclohexaneacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-04-21 | — | — | EP | disclosed |