Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PARP6 | Q2NL67 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299584 | 0.91 | HRH3 (0.42) | HRH3AOC3GPR119MEN1KMT2A | |
| SCHEMBL7296131 | 0.88 | AOC3 (0.38) | HRH3AOC3GPR119MEN1KMT2A | |
| SCHEMBL7297485 | 0.86 | MEN1 (0.45) | HRH3AOC3GPR119MEN1KMT2A | |
| SCHEMBL7344852 | 0.84 | ITGB3 (0.45) | HRH3AOC3GPR119MEN1KMT2A | |
| SCHEMBL7303451 | 0.83 | GPR119 (0.42) | HRH3AOC3GPR119MEN1KMT2A | |
| SCHEMBL7295272 | 0.83 | AOC3 (0.43) | HRH3AOC3GPR119MEN1KMT2A | |
| SCHEMBL7295259 | 0.83 | AOC3 (0.43) | HRH3AOC3GPR119MEN1KMT2A | |
| SCHEMBL7299587 | 0.82 | HRH3 (0.36) | HRH3AOC3GPR119MEN1KMT2A | |
| SCHEMBL7304758 | 0.80 | PANK3 (0.39) | HRH3AOC3GPR119MEN1KMT2A | |
| SCHEMBL7293154 | 0.79 | ALDH1A1 (0.34) | HRH3GPR119MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537980-A1 | Cyclohexaneacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-04-21 | — | — | EP | disclosed |