Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 5/20 | 0.34 |
| ▸ | CTSL | P07711 | 3/20 | 0.34 |
| ▸ | CTSK | P43235 | 3/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303451 | 0.88 | GPR119 (0.42) | ARGPR119AOC3JAK2JAK1 | |
| SCHEMBL7297025 | 0.84 | KMT2A (0.41) | ARGPR119CTSSCTSKIRAK4 | |
| SCHEMBL7296131 | 0.84 | AOC3 (0.38) | GPR119AOC3HRH3MEN1KMT2A | |
| SCHEMBL7295259 | 0.84 | AOC3 (0.43) | GPR119AOC3HRH3MEN1KMT2A | |
| SCHEMBL7295272 | 0.84 | AOC3 (0.43) | GPR119AOC3HRH3MEN1KMT2A | |
| SCHEMBL7299584 | 0.80 | HRH3 (0.42) | GPR119AOC3HRH3MEN1KMT2A | |
| SCHEMBL7305518 | 0.80 | HRH3 (0.42) | GPR119AOC3HRH3MEN1KMT2A | |
| SCHEMBL7299587 | 0.78 | HRH3 (0.36) | GPR119AOC3HRH3MEN1KMT2A | |
| SCHEMBL7305692 | 0.77 | ALK (0.40) | ARGPR119IRAK4HRH3 | |
| SCHEMBL7297485 | 0.76 | MEN1 (0.45) | GPR119AOC3HRH3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537980-A1 | Cyclohexaneacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-04-21 | — | — | EP | disclosed |