SCHEMBL9744805

SCHEMBL9744805

O=C(NC(Cc1ccc(O)c(O)c1)C(=O)O)OCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.58
ITGB3 P05106 9/20 0.57
ITGA2B P08514 8/20 0.57
ITGAV P06756 1/20 0.55
TACR1 P25103 2/20 0.54
CTSL P07711 2/20 0.54
CTSB P07858 2/20 0.54
CTSS P25774 2/20 0.54
CTSK P43235 1/20 0.53
MME P08473 1/20 0.53
ECE1 P42892 1/20 0.53
ALDH1A1 P00352 1/20 0.52
ALOX15 P16050 1/20 0.52
PPARG P37231 1/20 0.52
PPARA Q07869 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9744810 1.00 TYR (0.58) TYRITGB3ITGA2BITGAVTACR1
SCHEMBL30319896 1.00 TYR (0.58) TYRITGB3ITGA2BITGAVTACR1
SCHEMBL29559972 0.92 TYR (0.62) TYRTACR1CTSLCTSBCTSS
SCHEMBL7437357 0.92 TYR (0.62) TYRTACR1CTSLCTSBCTSS
SCHEMBL5802843 0.92 TYR (0.62) TYRTACR1CTSLCTSBCTSS
SCHEMBL2947377 0.90 LCK (0.61) TYRTACR1CTSLCTSBCTSS
SCHEMBL17294499 0.89 CA2 (0.57) TYRITGB3ITGA2BITGAVTACR1
SCHEMBL8586541 0.89 FOLH1 (0.58) TYRITGB3ITGA2BITGAVTACR1
SCHEMBL8586533 0.89 ITGB3 (0.57) TYRITGB3ITGA2BITGAVTACR1
SCHEMBL7296176 0.88 TYR (0.55) TYRITGB3ITGAVTACR1CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1931370-A Glycopeptide conjugate microsphere or microcapsule and its prepn process UNIV EAST CHINA SCIENCE & ENG (CN) 2007-03-21 CN claimed
US-20250213685-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2025-07-03 US disclosed
US-20250177374-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same ABBVIE INC (US) 2025-06-05 US disclosed
EP-4364754-A2 ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES AbbVie Inc. (US) 2024-05-08 EP disclosed
US-20240058450-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same ABBVIE INC (US) 2024-02-22 US disclosed
CN-109963870-B anti-B7-H3 antibodies and antibody drug conjugates 艾伯维公司 2023-07-28 CN disclosed
CN-116284404-A anti-B7-H3 antibodies and antibody drug conjugates 艾伯维公司 2023-06-23 CN disclosed
CN-116173232-A anti-CD 98 antibodies and antibody drug conjugates 艾伯维公司 2023-05-30 CN disclosed
CN-116059202-A anti-EGFR antibody drug conjugates 艾伯维公司 2023-05-05 CN disclosed
CN-116059201-A anti-EGFR antibody drug conjugates 艾伯维公司 2023-05-05 CN disclosed
US-20160339117-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same ABBVIE INC. (US) 2016-11-24 US disclosed
WO-2016094509-A1 BCL XL INHIBITORY COMPOUNDS HAVING LOW CELL PERMEABILITY AND ANTIBODY DRUG CONJUGATES INCLUDING THE SAME ABBVIE INC. (US) 2016-06-16 WO disclosed
CN-1931370-B Glycopeptide conjugate microsphere or microcapsule and its preparation process UNIV EAST CHINA SCIENCE & TECH 2010-09-15 CN disclosed
CN-1931370-A Glycopeptide conjugate microsphere or microcapsule and its prepn process UNIV EAST CHINA SCIENCE & ENG (CN) 2007-03-21 CN disclosed
EP-0309827-B1 L-DOPA DERIVATIVES OR THEIR ACID ADDITION SALTS, PROCESS FOR PRODUCING SAME AND THEIR USE BANYU PHARMACEUTICAL CO., LTD. (JP) 1992-01-02 EP disclosed
US-4966915-A L-dopa derivatives or their acid addition salts, process for producing same and their use BANYU PHARMACEUTICAL CO., LTD. (JP) 1990-10-30 US disclosed
EP-0309827-A1 L-Dopa derivatives or their acid addition salts, process for producing same and their use BANYU PHARMACEUTICAL CO., LTD. (JP) 1989-04-05 EP disclosed
EP-0268678-A1 NOVEL 5-FLUOROURIDINE COMPOUNDS AND PROCESS FOR THEIR PREPARATION FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-06-01 EP disclosed
US-4134991-A PARKINSON*S DISEASE, CARDIOVASCULAR DISORDERS, NEUROLEPTIC AGENTS SYNTHELABO (FR) 1979-01-16 US disclosed
US-3846476-A N-BENZYLOXYCARBONYL-DOPA DERIVATIVES HOFFMANN LA ROCHE 1974-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250213685-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES EGFR, ERBB2, ERBB3 TYR 3490/4885ITGB3 626/4885ITGA2B 908/4885
US-20160339117-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same BCL2, BAX, BCL9 TYR 4528/4885ITGB3 1899/4885ITGA2B 1865/4885
US-20250177374-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same BCL2, BAX, BCL9 TYR 4528/4885ITGB3 1899/4885ITGA2B 1865/4885
US-20240058450-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same BCL2, BAX, BCL9 TYR 4528/4885ITGB3 1899/4885ITGA2B 1865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.