SCHEMBL9744810

SCHEMBL9744810

O=C(N[C@@H](Cc1ccc(O)c(O)c1)C(=O)O)OCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.58
ITGB3 P05106 9/20 0.57
ITGA2B P08514 8/20 0.57
ITGAV P06756 1/20 0.55
TACR1 P25103 2/20 0.54
CTSL P07711 2/20 0.54
CTSB P07858 2/20 0.54
CTSS P25774 2/20 0.54
CTSK P43235 1/20 0.53
MME P08473 1/20 0.53
ECE1 P42892 1/20 0.53
ALDH1A1 P00352 1/20 0.52
ALOX15 P16050 1/20 0.52
PPARG P37231 1/20 0.52
PPARA Q07869 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30319896 1.00 TYR (0.58) TYRITGB3ITGA2BITGAVTACR1
SCHEMBL9744805 1.00 TYR (0.58) TYRITGB3ITGA2BITGAVTACR1
SCHEMBL29559972 0.92 TYR (0.62) TYRTACR1CTSLCTSBCTSS
SCHEMBL7437357 0.92 TYR (0.62) TYRTACR1CTSLCTSBCTSS
SCHEMBL5802843 0.92 TYR (0.62) TYRTACR1CTSLCTSBCTSS
SCHEMBL2947377 0.90 LCK (0.61) TYRTACR1CTSLCTSBCTSS
SCHEMBL17294499 0.89 CA2 (0.57) TYRITGB3ITGA2BITGAVTACR1
SCHEMBL8586541 0.89 FOLH1 (0.58) TYRITGB3ITGA2BITGAVTACR1
SCHEMBL8586533 0.89 ITGB3 (0.57) TYRITGB3ITGA2BITGAVTACR1
SCHEMBL7296176 0.88 TYR (0.55) TYRITGB3ITGAVTACR1CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250127167-A1 ANTIMICROBIAL PEPTIDES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2025-04-24 US claimed
EP-4401555-A1 ANTIMICROBIAL PEPTIDES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2024-07-24 EP claimed
WO-2023042201-A1 ANTIMICROBIAL PEPTIDES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2023-03-23 WO claimed
US-20250213685-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2025-07-03 US disclosed
US-20250177374-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same ABBVIE INC (US) 2025-06-05 US disclosed
US-20250127167-A1 ANTIMICROBIAL PEPTIDES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2025-04-24 US disclosed
CN-119176768-A Preparation method and application of catechol derivatives and administration and preparation device 海南大学 2024-12-24 CN disclosed
EP-4401555-A1 ANTIMICROBIAL PEPTIDES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2024-07-24 EP disclosed
EP-4364754-A2 ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES AbbVie Inc. (US) 2024-05-08 EP disclosed
US-20240058450-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same ABBVIE INC (US) 2024-02-22 US disclosed
CN-109963870-B anti-B7-H3 antibodies and antibody drug conjugates 艾伯维公司 2023-07-28 CN disclosed
EP-0237082-B1 3,5-DISUBSTITUTED 4,5-DIHYDROISOXAZOLES AS TRANSGLUTAMINASE INHIBITORS SYNTEX (U.S.A.) INC. (US) 1991-05-29 EP disclosed
US-4966915-A L-dopa derivatives or their acid addition salts, process for producing same and their use BANYU PHARMACEUTICAL CO., LTD. (JP) 1990-10-30 US disclosed
US-4929630-A SKIN DISORDERS, ACNE, 4,5-DIHYDROISOOXAZOLE PEPTIDES SYNTEX (U.S.A.) INC. (US) 1990-05-29 US disclosed
US-4912120-A Containing amine and amide substitution SYNTEX (U.S.A.) INC. (US) 1990-03-27 US disclosed
EP-0309827-A1 L-Dopa derivatives or their acid addition salts, process for producing same and their use BANYU PHARMACEUTICAL CO., LTD. (JP) 1989-04-05 EP disclosed
EP-0268678-A1 NOVEL 5-FLUOROURIDINE COMPOUNDS AND PROCESS FOR THEIR PREPARATION FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-06-01 EP disclosed
EP-0237082-A2 3,5-disubstituted 4,5-dihydroisoxazoles as transglutaminase inhibitors SYNTEX (U.S.A.) INC. (US) 1987-09-16 EP disclosed
US-3933859-A BLOOD PRESSURE LOWERING, SYMPATHECTOMY HOFFMANN-LA ROCHE, INC. (US) 1976-01-20 US disclosed
US-3846476-A N-BENZYLOXYCARBONYL-DOPA DERIVATIVES HOFFMANN LA ROCHE 1974-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250213685-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES EGFR, ERBB2, ERBB3 TYR 3490/4885ITGB3 626/4885ITGA2B 908/4885
US-20250177374-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same BCL2, BAX, BCL9 TYR 4528/4885ITGB3 1899/4885ITGA2B 1865/4885
US-20240058450-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same BCL2, BAX, BCL9 TYR 4528/4885ITGB3 1899/4885ITGA2B 1865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.