Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 2/20 | 0.47 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7296713 | 1.00 | PLA2G10 (0.47) | PLA2G10PLA2G5OPRM1OPRL1POLB | |
| SCHEMBL7285097 | 0.88 | PLA2G10 (0.60) | PLA2G10PLA2G5OPRM1OPRL1POLB | |
| Hydrochloric Acid SCHEMBL7285100 | 0.87 | PLA2G10 (0.59) | PLA2G10PLA2G5OPRM1OPRL1POLB | |
| Hydrochloric Acid SCHEMBL7285090 | 0.87 | PLA2G10 (0.59) | PLA2G10PLA2G5OPRM1OPRL1POLB | |
| SCHEMBL7278907 | 0.79 | PLA2G10 (0.45) | PLA2G10PLA2G5OPRM1OPRL1POLB | |
| Hydrochloric Acid SCHEMBL7278550 | 0.78 | PLA2G10 (0.44) | PLA2G10PLA2G5POLBPKMGAA | |
| SCHEMBL6181334 | 0.77 | PLA2G10 (0.53) | PLA2G10PLA2G5POLBPKMGAA | |
| Oxalic Acid SCHEMBL7298024 | 0.77 | PLA2G10 (0.41) | PLA2G10PLA2G5OPRM1OPRL1POLB | |
| Oxalic Acid SCHEMBL7298013 | 0.77 | PLA2G10 (0.41) | PLA2G10PLA2G5OPRM1OPRL1POLB | |
| SCHEMBL7296969 | 0.76 | PLA2G10 (0.43) | PLA2G10PLA2G5POLBPKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643072-B1 | 2-Piperazinone compounds and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-02-24 | — | — | EP | disclosed |
| US-5550131-A | ANTITHROMBOTIC AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0643072-A1 | 2-Piperazinone compounds and their use | Takeda Chemical Industries, Ltd. (JP) | 1995-03-15 | — | — | EP | disclosed |