Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 8/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
| ▸ | MVD | P53602 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6792962 | 0.90 | THRB (0.55) | THRBALOX12KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5544779 | 0.90 | THRB (0.55) | THRBALOX12KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6438383 | 0.84 | ACE (0.53) | THRBALOX12KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL13250828 | 0.84 | THRB (0.49) | THRBALOX12KMT2AALDH1A1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL6786573 | 0.82 | THRB (0.51) | THRBALOX12KMT2AACEACE2 | |
| SCHEMBL7290822 | 0.81 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2ACEACE2MVD | |
| SCHEMBL6436570 | 0.81 | ACE (0.49) | THRBALOX12KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL31710128 | 0.81 | DGAT1 (0.53) | THRBALOX12KMT2AACEACE2 | |
| SCHEMBL7288562 | 0.79 | ALDH1A1 (0.53) | KMT2AALDH1A1SMN1; SMN2MVD | |
| SCHEMBL6786583 | 0.78 | THRB (0.45) | THRBALOX12KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915088-B1 | D-Proline derivatives | HOFFMANN LA ROCHE (CH) | 2002-09-18 | — | — | EP | claimed |