Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7296884 | 0.93 | F10 (0.48) | CPB1HTR2CGAAHTTMEN1 | |
| SCHEMBL1938495 | 0.87 | LMNA (0.52) | CPB1HTR2CGAAHTTMEN1 | |
| SCHEMBL2261792 | 0.87 | LMNA (0.52) | CPB1HTR2CGAAHTTMEN1 | |
| SCHEMBL1938713 | 0.87 | LMNA (0.52) | CPB1HTR2CGAAHTTMEN1 | |
| SCHEMBL10563477 | 0.81 | ALDH1A1 (0.43) | HTR2CGAAMEN1KMT2AEPHX2 | |
| SCHEMBL7659939 | 0.81 | CPB1 (0.49) | CPB1GAAHTTMEN1KMT2A | |
| SCHEMBL1938499 | 0.79 | SMN1; SMN2 (0.55) | CPB1GAAHTTMEN1KMT2A | |
| SCHEMBL17335891 | 0.79 | MEN1 (0.43) | CPB1HTR2CGAAHTTMEN1 | |
| Hydrochloric Acid SCHEMBL17335888 | 0.78 | MEN1 (0.42) | CPB1HTR2CGAAMEN1KMT2A | |
| SCHEMBL2450751 | 0.78 | ALDH1A1 (0.65) | HTR2CALDH1A1MC4RUSP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445796-B1 | Derivatives of acetic acid containing peptide bonds | HOFFMANN LA ROCHE (CH) | 1998-06-17 | — | — | EP | disclosed |
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| US-5273982-A | An amidinoaryleneamidoalkylpiperazinyleneacetic acid | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |
| EP-0445796-A2 | Derivatives of acetic acid | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-11 | — | — | EP | disclosed |