Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | KDM1A | O60341 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1224023 | 0.83 | TP53 (0.71) | TP53MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7296951 | 0.83 | MAPT (0.80) | TP53MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9005244 | 0.83 | POLB (0.64) | TP53MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28246624 | 0.81 | NPC1 (0.68) | TP53MAPTNPC1RAB9ASMN1; SMN2 | |
| Benzyl Phenylcarbamate SCHEMBL1222943 | 0.81 | POLB (0.78) | TP53MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10447512 | 0.81 | L3MBTL1 (0.59) | MAPTNPC1RAB9ASMN1; SMN2PTPN1 | |
| SCHEMBL1223807 | 0.80 | RAB9A (0.67) | TP53MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6983615 | 0.80 | PPARA (0.60) | TP53MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1870929 | 0.79 | POLB (0.71) | TP53MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7294828 | 0.79 | MAPT (0.73) | TP53MAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | claimed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |