SCHEMBL729990

SCHEMBL729990

C=CCc1cccc2cc3ccccc3cc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.44
GABRB2 P47870 2/20 0.44
AKR1B1 P15121 1/20 0.38
ALDH1A1 P00352 6/20 0.38
KDM4E B2RXH2 4/20 0.38
GAA P10253 2/20 0.38
AURKA O14965 1/20 0.38
DAPK3 O43293 1/20 0.38
MAP4K4 O95819 1/20 0.38
RET P07949 1/20 0.38
IGF1R P08069 1/20 0.38
MET P08581 1/20 0.38
PIM1 P11309 1/20 0.38
LTK P29376 1/20 0.38
KDR P35968 1/20 0.38
MAPK8 P45983 1/20 0.38
MAPK9 P45984 1/20 0.38
CDK8 P49336 1/20 0.38
CLK2 P49760 1/20 0.38
CDK9 P50750 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anthracene SCHEMBL28476048 1.00 GABRA1 (0.44) GABRA1GABRB2AKR1B1ALDH1A1KDM4E
SCHEMBL30083979 1.00 GABRA1 (0.44) GABRA1GABRB2AKR1B1ALDH1A1KDM4E
SCHEMBL1116337 0.98 GABRA1 (0.43) GABRA1GABRB2AKR1B1ALDH1A1KDM4E
SCHEMBL6524646 0.98 GABRA1 (0.43) GABRA1GABRB2AKR1B1ALDH1A1KDM4E
Phenanthrene SCHEMBL28328083 0.93 ALDH1A1 (0.48) GABRA1GABRB2ALDH1A1AURKADAPK3
SCHEMBL29106731 0.86 GABRA1 (0.47) GABRA1GABRB2AKR1B1ALDH1A1KDM4E
SCHEMBL28280549 0.85 TLR8 (0.40) MTNR1AMTNR1BMAPT
SCHEMBL6402798 0.82 ALDH1A1 (0.35) GABRA1GABRB2ALDH1A1KDM4EGAA
SCHEMBL10479665 0.82 ALDH1A1 (0.34) ALDH1A1KDM4EGAAHSD17B10MEN1
SCHEMBL30083984 0.82 CYP1A2 (0.52) GABRA1GABRB2ALDH1A1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 369 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES ALCON INC (CH) 2026-01-01 US claimed
US-12379611-B2 Diffractive contact lenses ALCON INC. (CH) 2025-08-05 US claimed
CN-118165599-B Self-repairing flame-retardant coating and preparation method thereof 深圳嘉德高新材料有限公司 2024-11-15 CN claimed
CN-118165599-A Self-repairing flame-retardant coating and preparation method thereof 深圳嘉德高新材料有限公司 2024-06-11 CN claimed
EP-4356169-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-04-24 EP claimed
CN-117717902-A Preparation method and application of covalent organic framework nanofiltration membrane 天津大学 2024-03-19 CN claimed
CN-114906819-B Method for preparing anthraquinone derivative from anthracene and for producing hydrogen peroxide 中国石油化工股份有限公司 2024-03-12 CN claimed
CN-117280252-A Multifocal diffractive silicone hydrogel contact lenses 爱尔康公司 2023-12-22 CN claimed
CN-113462429-B Method for producing low-carbon olefin and aromatic hydrocarbon 中国石油化工股份有限公司 2023-03-24 CN claimed
CN-113462430-B Method for producing low-carbon olefin and multiple aromatic hydrocarbons from petroleum hydrocarbons 中国石油化工股份有限公司 2023-03-24 CN claimed
US-6273102-B1 Method of cleaning and maintaining petroleum refining plants SOFTARD INDUSTRIES CO., LTD. (JP) 2001-08-14 US claimed
US-6127324-A POLYALKYLENE GLYCOL IS MADE USING A NON-AMINE INITIATOR AND OPTIONALLY ESTERIFIED OR ETHERIFIED; OXIDATION AND THERMAL STABILITY, AND HYDROLYTIC STABILITY; USE AS A POSITIVE DISPLACEMENT COMPRESSOR LUBRICANT THE LUBRIZOL CORPORATION (US) 2000-10-03 US claimed
EP-0698823-B1 Antireflective coating for microlithography IBM (US) 1999-12-29 EP claimed
US-5736301-A USING DEEP ULTRAVIOLET RADIATION INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1998-04-07 US claimed
EP-0698823-A1 Antireflective coating for microlithography International Business Machines Corporation (US) 1996-02-28 EP claimed
EP-0192492-B1 PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1992-01-02 EP claimed
US-4912071-A Heat treatment with mixture od gas oil and aromatic hydrocarbon KASHIMA ENGINEERING CO., LTD. (JP) 1990-03-27 US claimed
US-4113765-A Continuous process for sulfonating alkyl aromatics STANDARD OIL COMPANY (INDIANA) (US) 1978-09-12 US claimed
US-4014728-A Method of making an imaging member XEROX CORPORATION (US) 1977-03-29 US claimed
US-3979495-A Method of making a photoreceptor XEROX CORPORATION (US) 1976-09-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES LBR, CRYZ, CRYAA GABRA1 473/4885GABRB2 622/4885AKR1B1 3798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.