Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 2/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300635 | 0.86 | TNKS (0.30) | TNKS | |
| SCHEMBL7298334 | 0.84 | TNKS (0.33) | LMNATNKSMAPTSMN1; SMN2 | |
| SCHEMBL7378273 | 0.83 | CDK8 (0.32) | — | |
| SCHEMBL7292763 | 0.83 | SMN1; SMN2 (0.36) | TNKSSMN1; SMN2 | |
| SCHEMBL7297727 | 0.83 | TDP1 (0.37) | LMNAMAPT | |
| SCHEMBL7301120 | 0.82 | NR4A2 (0.31) | LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7299641 | 0.81 | HRH4 (0.33) | — | |
| SCHEMBL7300227 | 0.81 | MEN1 (0.37) | MAPTSMN1; SMN2 | |
| SCHEMBL7375797 | 0.81 | NPC1 (0.32) | TNKS | |
| SCHEMBL7292929 | 0.79 | NPBWR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308792-B1 | AZACHROMANE DERIVATIVES | MERCK PATENT GmbH (DE) | 1993-07-28 | — | — | EP | disclosed |
| US-4931454-A | Azachroman derivatives with effects on the cardiovascular system | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-06-05 | — | — | US | disclosed |
| EP-0308792-A2 | Azachromane derivatives | MERCK PATENT GmbH (DE) | 1989-03-29 | — | — | EP | disclosed |