Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.78 |
| ▸ | ACE | P12821 | 4/20 | 0.78 |
| ▸ | ECE1 | P42892 | 3/20 | 0.78 |
| ▸ | NPPA | P01160 | 1/20 | 0.78 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.38 |
| ▸ | MMP1 | P03956 | 4/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sampatrilat SCHEMBL4567110 | 0.88 | ECE1 (1.00) | MMEACEECE1NPPAITGB1 | |
| Sampatrilat SCHEMBL7301333 | 0.88 | ECE1 (1.00) | MMEACEECE1NPPAITGB1 | |
| Sampatrilat SCHEMBL49066 | 0.88 | ECE1 (1.00) | MMEACEECE1NPPAITGB1 | |
| SCHEMBL7293863 | 0.85 | MME (0.77) | MMEACEECE1NPPAITGB1 | |
| SCHEMBL7293844 | 0.85 | MME (0.77) | MMEACEECE1NPPAITGB1 | |
| SCHEMBL7293852 | 0.85 | MME (0.77) | MMEACEECE1NPPAITGB1 | |
| SCHEMBL6441043 | 0.85 | ACE (0.81) | MMEACEECE1NPPAERAP2 | |
| SCHEMBL7294367 | 0.83 | ACE (0.91) | MMEACEECE1NPPAMMP1 | |
| SCHEMBL7322680 | 0.83 | MME (0.66) | MMEACEECE1NPPAITGB1 | |
| SCHEMBL7302883 | 0.82 | MME (0.82) | MMEACEECE1NPPAITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358398-A1 | Cycloalkyl-substituted glutaramide antihypertensive agents | Pfizer Limited (GB) | 1990-03-14 | — | — | EP | disclosed |