Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4050701 | 0.71 | PBK (0.41) | METAP2METAP1 | |
| SCHEMBL4059999 | 0.68 | METAP2 (0.38) | METAP2METAP1 | |
| SCHEMBL4054581 | 0.68 | ADORA1 (0.40) | METAP2METAP1 | |
| SCHEMBL4055604 | 0.65 | METAP2 (0.35) | METAP2METAP1 | |
| SCHEMBL4044959 | 0.61 | EGLN1 (0.40) | — | |
| SCHEMBL8388260 | 0.60 | SLC6A4 (0.49) | — | |
| SCHEMBL4040136 | 0.58 | AAK1 (0.43) | METAP2METAP1 | |
| SCHEMBL4048041 | 0.58 | PBK (0.40) | METAP2METAP1 | |
| Zarzissine SCHEMBL1514280 | 0.58 | NUDT1 (0.50) | METAP2METAP1 | |
| SCHEMBL14409054 | 0.58 | METAP2 (0.44) | METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137876-A | NUCLEOSIDE ANTIVIRAL AND ANTI-INFLAMMATORY COMPOUNDS AND COMPOSITIONS AND METHODS FOR USING SAME | MERCK & CO., INC. (US) | 1992-08-11 | — | — | US | disclosed |
| EP-0480713-A1 | Nucleoside antiviral and immunomodulating agents | MERCK & CO. INC. (US) | 1992-04-15 | — | — | EP | disclosed |