Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90B1 | P14625 | 5/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7291292 | 0.84 | AR (0.40) | HSP90B1HSP90AA1HSP90AB1RAB9ANPC1 | |
| SCHEMBL7299707 | 0.77 | TSHR (0.53) | HSP90B1HSP90AA1HSP90AB1RAB9ANPC1 | |
| SCHEMBL17381155 | 0.75 | RAB9A (0.57) | HSP90B1HSP90AA1HSP90AB1RAB9ANPC1 | |
| SCHEMBL7299362 | 0.74 | HPGD (0.48) | SMN1; SMN2KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL696380 | 0.71 | OPRD1 (0.52) | HSP90B1HSP90AA1HSP90AB1RAB9ANPC1 | |
| SCHEMBL7298713 | 0.69 | MAPT (0.53) | HSP90AA1SMN1; SMN2KMT2AMEN1AR | |
| SCHEMBL8503637 | 0.68 | RAB9A (0.55) | HSP90B1HSP90AA1HSP90AB1RAB9ANPC1 | |
| SCHEMBL1593910 | 0.68 | SMN1; SMN2 (0.55) | RAB9ANPC1SMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL10178199 | 0.68 | HSP90AA1 (0.51) | HSP90B1HSP90AA1HSP90AB1OPRD1OPRK1 | |
| SCHEMBL13379459 | 0.68 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300688-A1 | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them | FISONS plc (GB) | 1989-01-25 | — | — | EP | disclosed |