Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | NAMPT | P43490 | 5/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307274 | 0.86 | ITGB3 (0.60) | DRD2ABCB1ABCG2MEN1KMT2A | |
| SCHEMBL7298730 | 0.82 | KDM4E (0.54) | KDM4EALDH1A1DRD2ROCK2PRKAA2 | |
| Hydrochloric Acid SCHEMBL7323352 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1DRD2ROCK2PRKAA2 | |
| SCHEMBL7300010 | 0.80 | ITGB3 (0.68) | ABCB1ABCG2ITGB3ITGA2B | |
| SCHEMBL7306830 | 0.79 | ACACB (0.48) | KDM4EALDH1A1DRD2MEN1KMT2A | |
| SCHEMBL7299565 | 0.79 | NR1H2 (0.44) | KDM4EALDH1A1DRD2MEN1KMT2A | |
| SCHEMBL7312182 | 0.79 | MCHR1 (0.54) | DRD2NAMPTITGB3ITGA2B | |
| SCHEMBL12277410 | 0.76 | NR1H2 (0.43) | KDM4EALDH1A1DRD2MEN1KMT2A | |
| SCHEMBL4418240 | 0.76 | S1PR1 (0.56) | KDM4EALDH1A1DRD2RAB9AITGB3 | |
| SCHEMBL773073 | 0.75 | DRD2 (0.64) | KDM4EALDH1A1DRD2DRD3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |