Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | SOX18 | P35713 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16825144 | 0.92 | RAB9A (0.47) | CYP1A2SLC1A3SLC1A2SLC1A1MRGPRX4 | |
| SCHEMBL7301887 | 0.87 | PLAU (0.49) | PLAUCYP1A2FFAR1SOX18SLC13A5 | |
| SCHEMBL915503 | 0.79 | RAB9A (0.50) | CYP1A2SLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL698616 | 0.78 | TSHR (0.48) | CYP1A2RAB9AKMT2A | |
| SCHEMBL15961256 | 0.76 | TSHR (0.46) | CYP1A2RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL7385052 | 0.76 | AGXT (0.46) | CYP1A2RAB9AKMT2A | |
| SCHEMBL8670812 | 0.76 | PLAU (0.59) | PLAUCYP1A2ALOX5SOX18KMT2A | |
| SCHEMBL7295889 | 0.75 | AKR1B1 (0.51) | CYP1A2SLC1A3SLC1A2SLC1A1FFAR1 | |
| SCHEMBL29255545 | 0.74 | PTGS1 (0.59) | CYP1A2ALOX5RAB9AFFAR1 | |
| Ethylene Glycol SCHEMBL28921702 | 0.73 | TSHR (0.43) | CYP1A2RAB9AKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35886-E | ENDOTHELIN-CONVERTING ENZYME INHIBITOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-01 | — | — | US | disclosed |
| EP-0518299-B1 | Phosphonic acid derivatives, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-10-08 | — | — | EP | disclosed |
| US-5330978-A | Cardiovascular disorders, hypotensive agents, vasodilation | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-07-19 | — | — | US | disclosed |
| EP-0518299-A2 | Phosphonic acid derivatives, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-16 | — | — | EP | disclosed |